[Answer] 4. Caused by a destruction of cells in the substantia nigra region of the brain, this movement disorder is characterized by a shuffling gait, tremor and rigidity.

Step 1 : Introduction to the question "4. Caused by a destruction of cells in the substantia nigra region of the brain, this movement disorder is characterized by a shuffling gait, tremor and rigidity."

...1. Purkinje's disease 2. Pseudoparalysis of Parrot 3. Peutz-Jeghers syndrome 4. Parkinson's disease Parkinson's is relatively common; the actor Michael J. Fox is affected and has spoken openly about the condition. The neurotransmitter dopamine is reduced, so medical treatments include drugs that replace dopamine or reduce its breakdown.

Step 2 : Answer to the question "4. Caused by a destruction of cells in the substantia nigra region of the brain, this movement disorder is characterized by a shuffling gait, tremor and rigidity."

Parkinson's disease:

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